A guide to web tools to prioritize candidate genes
نویسندگان
چکیده
منابع مشابه
A guide to web tools to prioritize candidate genes
Finding the most promising genes among large lists of candidate genes has been defined as the gene prioritization problem. It is a recurrent problem in genetics in which genetic conditions are reported to be associated with chromosomal regions. In the last decade, several different computational approaches have been developed to tackle this challenging task. In this study, we review 19 computat...
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Background: Identifying disease gene from a list of candidate genes is an important task in bioinformatics. The main strategy is to prioritize candidate genes based on their similarity to known disease genes. Most of existing gene prioritization methods access only one genomic data source, which is noisy and incomplete. Thus, there is a need for the integration of multiple data sources containi...
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ژورنال
عنوان ژورنال: Briefings in Bioinformatics
سال: 2010
ISSN: 1467-5463,1477-4054
DOI: 10.1093/bib/bbq007